Papers with International Classification of Diseases

18 papers
AnEMIC: A Framework for Benchmarking ICD Coding Models (2022.emnlp-demos)

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Challenge: Diagnostic coding is the task of assigning diagnosis codes defined by the ICD (International Classification of Diseases) standard to patient visits based on clinical notes.
Approach: They propose to use an ICD coding framework to train and benchmark models . they correct errors in preprocessing and provide an interactive demo to analyze the models based on custom inputs.
Outcome: The framework corrects errors in preprocessing and provides key models and weights trained on correctly preprocessed datasets.
Intriguing Effect of the Correlation Prior on ICD-9 Code Assignment (2023.acl-srw)

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Challenge: The Ninth Revision of the International Classification of Diseases (ICD-9) is a standardized coding system used worldwide to classify and code diseases, injuries, and other health conditions.
Approach: They evaluate the usefulness of correlation bias and suggest it could improve ICD-9 code assignment in some cases.
Outcome: The proposed model improves on classes that are more imbalanced and less correlated with other codes, but the effect on individual class can be negative or positive.
DRGCoder: Explainable Clinical Coding for the Early Prediction of Diagnostic-Related Groups (2023.emnlp-demo)

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Challenge: Medical claim coding is the process of transforming medical records into structured codes in a classification system such as ICD-10 (International Classification of Diseases, Tenth Revision) or DRG (Diagnosis-Related Group) codes.
Approach: They propose an explainability-enhanced clinical claim coding system for the early prediction of medical severity DRGs (MS-DRGs) a novel multi-task Transformer model allows users to inspect DRGCoder’s reasoning by visualizing the weights for each word of the input.
Outcome: The proposed system allows users to analyze the weights of the input and compare across multiple discharge summaries.
MedCodER: A Generative AI Assistant for Medical Coding (2025.naacl-industry)

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Challenge: Medical coding is time-consuming and error-prone due to large label space, lengthy text inputs, and the absence of supporting evidence annotations.
Approach: They propose a Generative AI framework for automatic medical coding that leverages extraction, retrieval, and re-ranking techniques as core components.
Outcome: The proposed framework outperforms existing methods on the International Classification of Diseases (ICD) code prediction scale.
A Neural Architecture for Automated ICD Coding (P18-1)

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Challenge: Medical coding is time-consuming, expensive, and error prone.
Approach: They propose to use diagnosis descriptions (DDs) of a patient as inputs to select the most relevant ICD codes.
Outcome: The proposed algorithms perform on a clinical dataset with 59K patient visits.
Accurate and Well-Calibrated ICD Code Assignment Through Attention Over Diverse Label Embeddings (2024.eacl-long)

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Challenge: Existing approaches to assigning ICD codes to clinical text are time-consuming, labor intensive, and error-prone.
Approach: They propose to adapt a Transformer-based model to a longformer model and use it to encode clinical narratives.
Outcome: The proposed approach outperforms current state-of-the-art models in ICD coding with the label embeddings contributing to the good performance.
Auxiliary Knowledge-Induced Learning for Automatic Multi-Label Medical Document Classification (2024.lrec-main)

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Challenge: Existing methods for ICD indexing use machine learning to assign subset of codes to medical records . experimental results show proposed method achieves state-of-the-art performance on a number of measures.
Approach: They propose a method that uses a deep dilated residual convolution encoder to learn document representations across different lengths of the texts.
Outcome: The proposed method achieves state-of-the-art performance on a number of measures.
Fusion: Towards Automated ICD Coding via Feature Compression (2021.findings-acl)

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Challenge: Existing methods to assign ICD codes from unstructured clinical notes are noisy and prone to errors.
Approach: They propose a feature compressed ICD coding model called Fusion to address this problem.
Outcome: The proposed model outperforms existing models on two widely used datasets.
Travel on the ICD Tree: Benchmarking Agentic Reasoning for ICD Coding from Chinese Electronic Medical Records (2026.findings-acl)

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Challenge: Accurate International Classification of Diseases (ICD) coding is crucial for hospital management and healthcare data governance.
Approach: They propose a framework to evaluate ICD coding based on complete EMRs . they use a dataset of 560 real clinical records covering 434 common diseases .
Outcome: The proposed framework explores the capability boundaries of large language models under different paradigms.
Evaluation and LLM-Guided Learning of ICD Coding Rationales (2026.eacl-long)

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Challenge: Existing studies on the explainability of ICD coding rely on attention-based rationales and qualitative assessments conducted by physicians.
Approach: They propose to evaluate the explainability of rationales in ICD coding using a multi-granular rationale-annotated dataset.
Outcome: The proposed model improves the explainability of rationales in ICD coding by using human-annotated rationale-announced rationale models.
Automatic ICD Coding Exploiting Discourse Structure and Reconciled Code Embeddings (2022.coling-1)

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Challenge: Existing studies did not exploit the discourse structure of clinical notes, which provides rich contextual information for code assignment.
Approach: They propose to leverage section type classification and section type embeddings to exploit the discourse structure of clinical notes to generate rich contextual information for code assignment.
Outcome: The proposed model outperforms state-of-the-art models on a MIMIC dataset by a large margin.
Multi-stage Retrieve and Re-rank Model for Automatic Medical Coding Recommendation (2024.naacl-long)

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Challenge: Existing methods for ICD indexing have a heavy label distribution and a manual process . Xie and Xing (2017) propose a new approach to ICD re-ranking .
Approach: They propose a "retrieve and re-rank" framework to allocate subsets of ICD codes to medical records . they leverage auxiliary knowledge of the electronic health records (EHR) and a discrete retrieval method .
Outcome: The proposed method achieves state-of-the-art performance on the MIMIC-III benchmark.
HyperCore: Hyperbolic and Co-graph Representation for Automatic ICD Coding (2020.acl-main)

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Challenge: Existing methods for ICD coding ignore Code Hierarchy and Code Co-occurrence . cost of manual coding estimated to be $25 billion per year in the US .
Approach: They propose a hyperbolic representation method to leverage the code hierarchy and a graph convolutional network to utilize the code co-occurrence.
Outcome: The proposed model outperforms state-of-the-art methods on two widely used datasets.
A Two-Stage Decoder for Efficient ICD Coding (2023.findings-acl)

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Challenge: Recent automated ICD coding efforts improve performance by encoding medical notes and codes with additional data and knowledge bases.
Approach: They propose a two-stage decoding mechanism to predict ICD codes using hierarchical properties of the codes to split the prediction into two steps: at first, predict the parent code and then predict the child code based on the previous prediction.
Outcome: Experiments on the public MIMIC-III data show that the proposed model performs well in single-model settings without external data or knowledge.
Data Drift in Clinical Outcome Prediction from Admission Notes (2024.lrec-main)

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Challenge: a pivotal dataset for clinical NLP research was released in 2016 . public access to such datasets is limited due to privacy and ethical concerns .
Approach: They propose a novel clinical outcome prediction dataset based on MIMIC-IV . they provide initial insights into the performance of models trained on MIDIC-III .
Outcome: The proposed dataset aims to probe the robustness and generalization of clinical outcome prediction models . the study focuses on challenges tied to evolving documentation standards and changing codes in the ICD taxonomy .
Analyzing Code Embeddings for Coding Clinical Narratives (2021.findings-acl)

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Challenge: Recent work on automated ICD coding learn mappings between low-dimensional representations of clinical text reports and codes.
Approach: They propose novel neural networks for encoding medical codes based on textual, structural and statistical characteristics using a single deep learning baseline model.
Outcome: The proposed methods improve the accuracy of medical codes based on their textual, structural and statistical characteristics.
Set to Ordered Text: Generating Discharge Instructions from Medical Billing Codes (D19-1)

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Challenge: a neural architecture learns to generate content in a specific order without explicit specifications of the relations between input entities and output entities.
Approach: They propose a natural language generation task that generates discharge instructions from ICD codes . they propose to model content ordering and text generation in a specific order .
Outcome: The proposed model outperforms baseline models in BLEU scores and human evaluation.
ICDAGENT: Empowering Agentic Large Language Models for Explainable Medical Coding (2026.acl-long)

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Challenge: Existing models lack convincing, human-understandable explanations, making them difficult for physicians to trust and use in practice.
Approach: They propose a framework that aims to automatically assign ICD codes to clinical notes while providing explicit justifications for each assignment.
Outcome: The proposed framework achieves effective ICD coding with accurate explanations using two collaborative LLM agents: a coding agent and a critical agent.

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